Through digital-first process design, CMAC researchers decrease the material required for API development by an order of magnitude.
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Researchers at Eli Lilly & Company have successfully applied CMAC’s impurity rejection workflow in clinical development, achieving up to 100% rejection of problematic impurities.
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Model-based Digitalisation Framework Development for Continuous Manufacturing Processes
Workflows for the Application of a User-friendly Mechanistic Modelling Toolkit
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Considerable time has been spent as part of the EPSRC CMAC CIM research campaign, designing and implementing a workflow for continuous cooling crystallisation.
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This research explores possibilities to align future value network configurations and disruptive shifts in manufacturing and information technologies.
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Computer Aided Process Design (CAPD) and simulation tools have been successfully implemented in the chemical and oil industries since the early 60s to accelerate development and optimise the design and operation of process.
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Along with nucleation and growth, agglomeration is a commonly occurring process in crystallisation operations.
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The “Make To Order Processing Plants” (MOPPs) project involving CMAC, CPI, AstraZeneca and led by Perceptive Engineering.
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The particle engineering research group under the supervision of Prof Jan Sefcik has designed and investigated a novel continuous seed production unit.
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In the production of many materials solid state variation is recognised as a key issue.
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In the production of many materials solid state variation is recognised as a key issue.
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