Funding Announcement: Community for Analytical Measurement Science (CAMS) Industry Project
Funding Announcement
Dr Daniel Markl, CMAC University of Strathclyde, and Dr Ibrahim Khadra, SIPBS University of Strathclyde, are excited to announce the new £300,000 Industry Project from Community for Analytical Measurement Science (CAMS) titled ‘Understanding long-term stability of solid pharmaceutical dosage forms by characterisation of the composite materials at short (nano) scale length scales to enable modelling and prediction of emergent time-dependent physico-chemical changes’.
This is a collaborative project between the University of Strathclyde, AstraZeneca and Pfizer and will focus on the development of multi-scale models and a comprehensive understanding of the link between material attributes, the temporal nano- and microstructural evolution of pharmaceutical tablets and its effect on the in-vitro drug release performance. The project aims to deliver innovative digital tools that are capable of predicting long-term changes of drug release kinetics. The project will thus make a significant contribution towards the delivery of digitally enabled R&D, manufacturing and supply with benefits from reduced cost, environmental impact and improved health.
“We are delighted to announce this new project with AstraZeneca and Pfizer. This project allows us to develop predictive capabilities in physical stability of pharmaceutical tablets. We aim to develop fundamental understanding of physical changes of pharmaceutical tablets when they are stored with the final goal of delivering digital tools capable of predicting long-term changes of the performance of our most common medicines. These developments are a critical item in accelerating the development of new drug products while ensuring patients receive only safe and high quality medicines. This project will therefore not only benefit the pharmaceutical industry but also patients.”